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Important Safety Concerns With Razadyne

Specific Precautions and Warnings for Razadyne

Razadyne warnings and precautions to be aware of prior to taking the medicine include the following:
  • Two studies of Razadyne in people with mild cognitive impairment (not Alzheimer's disease) suggested that Razadyne may increase the risk of death. Deaths were due to a variety of causes with no definite pattern. Other studies have failed to confirm such findings. Be sure to discuss this possible risk with your healthcare provider if you take Razadyne for mild cognitive impairment. Razadyne is not approved for treating mild cognitive impairment.
  • Razadyne may affect the heart, possibly causing a dangerously slow heart rate. This is probably more common in people with heart conditions but can occur in people without any heart problems.
  • Razadyne may increase the production of stomach acid, increasing the risk of stomach or intestinal ulcers. If you have an ulcer (or a history of an ulcer), your healthcare provider should monitor you closely to make sure Razadyne is not making these problems worse.
  • The liver and kidneys help to clear Razadyne from the body. If you have liver or kidney disease, your body may not handle Razadyne as well as normal, and a lower Razadyne dosage may be recommended.
  • Razadyne can impair the ability of the bladder to empty, causing difficulty urinating. Let your healthcare provider know if you develop any bladder problems while taking Razadyne.
  • It is possible that Razadyne could cause seizures or make seizures worse. However, Alzheimer's disease itself may also cause seizures.
  • Stopping Razadyne (or decreasing the dose) suddenly can lead to a worsening of Alzheimer's symptoms.
  • Razadyne may cause a worsening of asthma symptoms. Check with your healthcare provider before taking Razadyne if you have asthma.
  • If you have a surgery planned, make sure to let your surgeon and anesthesiologist know you are taking Razadyne, as Razadyne can interact with some medications used during anesthesia.
  • Razadyne can potentially interact with several medications (see Razadyne Drug Interactions).
  • Razadyne is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not known (see Razadyne and Pregnancy).
  • It is not known whether Razadyne passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Razadyne and Breastfeeding).
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