There is currently no standard recommended phosphatidylserine dosage. In studies, doses of 100 mg three times daily have been used to treat Alzheimer's disease, dementia, and age-related declines in cognitive function. Studies have also used doses of 200 to 300 mg daily for ADHD treatment. However, it is not known whether these are the most effective and safe phosphatidylserine doses.
Phosphatidylserine is a naturally occurring molecule important for brain function. It is also used in dietary supplements. It is important to note that unlike medications (for which the standard doses have been well established), there is less information for determining the best dose for supplements, including phosphatidylserine.
In studies, phosphatidylserine doses of 100 mg three times daily have been used to treat Alzheimer's disease, dementia, and age-related declines in cognitive function. For ADHD treatment, studies have used phosphatidylserine doses of 200 to 300 mg daily. It is not known if these doses are the best (most effective and safe) doses for phosphatidylserine.
Because good information for phosphatidylserine dosing is lacking, it is reasonable to simply follow the instructions on the label of your particular phosphatidylserine product. Remember, though, that dietary supplements (including phosphatidylserine) can be sold in the United States without any evidence that they are safe and effective. There is no guarantee that the phosphatidylserine dose recommended on the label is either safe or effective for any use.
When choosing a phosphatidylserine dosage, keep in mind that phosphatidylserine is found in many foods and is made by the human body.