NADH

NADH is a molecule that is produced naturally by the body. It functions as a coenzyme and helps with many chemical reactions in the body. As a supplement, NADH supposedly helps treat a wide range of conditions, from depression to jet lag to high cholesterol. However, there is no scientific evidence supporting the effectiveness of NADH for these uses.

 

What Is NADH?

NADH (nicotinamide adenine dinucleotide hydrate) is a naturally occurring molecule found throughout the human body. It is not considered to be a vitamin, since the body can make its own NADH. It is also used as an ingredient in dietary supplements and has been claimed to help with the following conditions:
 
These are just some of the reported uses of NADH. It is often promoted as a supplement for general health and nutritional enhancement.
 
(Click NADH Benefits for more information on what NADH is used for.)
 

How Does NADH Work?

NADH is a molecule that works as a coenzyme in the human body. Coenzymes help other enzymes work in chemical reactions. Many essential chemical reactions in the body use NADH. It is not known exactly how NADH supplementation could work for various conditions, especially since the body can make NADH on its own. NADH may have antioxidant activity, and this may be one way that it works for various conditions.
 

Is NADH Effective?

At this time, there is not enough scientific evidence available to suggest that NADH is truly effective for any use.
 
(Click Does NADH Work? for more information.)
 

Dosing Information for NADH

The best dosage for NADH has not yet been established, since the supplement has not been thoroughly studied.
 
(Click NADH Dosage for more information.)
 

Side Effects of NADH

There are no known side effects NADH. However, this probably reflects a lack of clinical studies on NADH, not a real absence of side effects.
 
(Click NADH Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
 

Drug Interactions With NADH

At this time, it is not known if NADH interacts with other supplements or medications (see NADH Drug Interactions).
 

Is NADH Safe?

Some people may be more likely to experience problems with NADH than others. Therefore, you should talk with your healthcare provider before taking it if you have:
 
  • Liver disease, such as liver failure, cirrhosis, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Any other serious or chronic health condition
  • Any allergies, including allergies to medications, foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click NADH Safety for more information, including any available NADH warnings and precautions.)
 

What If I Take an Overdose of NADH?

It is not known what exactly to expect from an overdose of NADH. If you think you may have taken too much, seek immediate medical attention.
 
(Click NADH Overdose for more information.)
 

How Should NADH Be Stored?

Refer to the label of your individual NADH product for information on how best to store it. Keep NADH and all other medications or supplements out of the reach of children.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;