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NADH Safety

People considering supplementation may wonder if NADH is safe. Although it is a naturally occurring molecule in the human body, there are still NADH safety precautions and warnings to be aware of regarding the supplements. For example, people with liver or kidney disease should talk to their healthcare provider prior to taking NADH.

Is NADH Safe?

NADH (nicotinamide adenine dinucleotide hydrate) is a dietary supplement used to treat a variety of different conditions. In order to use NADH safely, you should talk with your healthcare provider prior to taking it if you have:
  • Liver disease, such as liver failure, cirrhosis, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Any other serious or chronic health condition
  • Any allergies, including allergies to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also be sure to tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific NADH Warnings and Precautions

Warnings and precautions to be aware of concerning the safety of NADH include the following:
  • Supplements (including NADH) are not as closely regulated as drugs are. In fact, supplements can be sold in the United States without ever having been shown to be safe or effective.
  • If you have liver or kidney disease, check with your healthcare provider before taking any medication or supplement, including NADH. The liver and kidneys help clear many medications and supplements from the body.
  • Check with your healthcare provider before taking NADH (or any other dietary supplement) if you have any chronic or serious medical conditions.
  • It is not known if NADH supplements interact with other supplements or medications (see NADH Drug Interactions for more information).
  • It is not known if NADH is safe for pregnant or breastfeeding women (see NADH and Pregnancy and NADH and Breastfeeding).
  • If you decide to use supplements, be aware that what you see on the label may not reflect what is in the bottle. For example, some dietary supplements have been found to be contaminated with heavy metals or prescription drugs, and some have been found to have much more or much less of the featured ingredient than their label states. Therefore, make sure the manufacturer of your NADH product is trusted and reputable. It is a good sign if a manufacturer abides by the rules of Good Manufacturing Practices (GMP) for drugs. It is also a good sign if a product has the United States Pharmacopoeia (USP) seal, which means that the product has been independently tested and shown to contain the correct ingredients in the amounts listed on the label. Your pharmacist is a good resource for information about which manufacturers are most reputable.
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NADH Supplement Information

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