Available by prescription, Namenda XR is licensed for the treatment of Alzheimer's disease. It comes in the form of an extended-release capsule, and is only taken once a day. This medication is not suitable for everyone; make sure your healthcare provider is aware of any other medical conditions you may have and any other medications you are taking. Side effects may include diarrhea, headaches, and dizziness.
Namenda XR is made by Forest Pharmaceuticals, Inc.
How Does It Work?
Namenda XR is classified as an NMDA receptor antagonist. "NMDA" stands for N-methyl-D-asparate. It is thought that some of the symptoms of Alzheimer's may be related to changes in NMDA receptors that allow for abnormal, excessive excitation of the receptors by glutamate (a neurotransmitter brain chemical).
Namenda XR works by binding to the NMDA receptor and preventing excessive excitation by glutamate. Currently, no other Alzheimer's medications work like Namenda XR, other than the short-acting version, Namenda.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed October 1, 2010.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
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