Alzheimers Home > More Info on Namenda XR Indications

How Does Namenda XR Work?

Namenda XR is classified as an NMDA receptor antagonist. "NMDA" stands for N-methyl-D-asparate. It is thought that some of the symptoms of Alzheimer's may be related to changes in NMDA receptors that allow for abnormal, excessive excitation of the receptors by glutamate (a neurotransmitter brain chemical).
 
Namenda XR works by binding to the NMDA receptor and preventing excessive excitation by glutamate. Currently, no other Alzheimer's medications work like Namenda XR, other than the short-acting version, Namenda.
 

Can Children Use It?

Namenda XR is not approved for use in "pediatric patients" (usually defined as individuals under the age of 18).
 

Off-Label Uses for Namenda XR

On occasion, your healthcare provider may recommend this product for something other than Alzheimer's disease (this would be known as an "off-label" use). Based on the off-label uses of short-acting memantine (Namenda), possible off-label uses for Namenda XR might include:
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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