Alzheimers Home > Does NADH Work?

People considering supplementation may wonder if NADH is effective. While studies have not determined conclusively that NADH works for any medical condition or for general nutritional supplementation, this does not mean that it couldn't work. Larger clinical studies and in-depth research on NADH is needed before its effectiveness can be known.

Does NADH Really Work?

NADH (nicotinamide adenine dinucleotide hydrate) is a naturally occurring molecule found throughout the human body. It is essential for many different chemical reactions in the body, which has led some people to believe that NADH supplementation may be beneficial. As a result, NADH is available in dietary supplements. Such supplements are often claimed to work for many different conditions. However, most of these claims have no scientific basis.

NADH Research and Clinical Studies

NADH supplementation has been studied only a little. The few studies that have been done generally have shown negative or unconvincingly positive results. In particular, early research suggests that NADH probably does not work for Alzheimer's disease. One preliminary study showed some promise for using NADH to treat chronic fatigue syndrome, but this study was small and not designed to prove that NADH really works for this condition. Early studies of NADH for Parkinson's disease have shown conflicting results.
There is not enough reliable scientific evidence to suggest that NADH works for any medical condition or for general nutritional supplementation. This does not mean that NADH does not work; it simply means that currently there is not any real proof that it does work. Some people (including most healthcare providers) feel that it is appropriate to take only medications and supplements that have been conclusively shown to be beneficial and safe. Other people, however, are comfortable experimenting with unproven treatments. Whether you decide to take NADH will largely depend on your willingness to try an unproven supplement that has not been shown to work for any condition.
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Last reviewed by: Kristi Monson, PharmD;
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