Cognex
® (
tacrine hydrochloride) is a prescription medication approved to treat mild to moderate
Alzheimer's disease. Although the medication is not a cure for
Alzheimer's disease, it can help slow down the worsening of
Alzheimer's symptoms (and may even temporarily improve such symptoms).
Cognex is made by Sciele Pharma, Inc.
Cognex is classified as an acetylcholinesterase inhibitor. It works by preventing a specific enzyme (known as acetylcholinesterase) from breaking down acetylcholine in the brain. Acetylcholine is a chemical that aids in many brain functions, including memory, attention, reason, and language. Problems with inadequate acetylcholine in the brain may be responsible for some of the
symptoms of Alzheimer's disease.
Cognex has been evaluated for Alzheimer's disease in several different studies.
These studies showed that people taking the drug often had a slower rate of decline in cognitive function ("thinking" functions, such as memory, language, and social interaction), compared to people taking a placebo (a "sugar pill" with no active ingredients). In general, a slight improvement was initially seen, followed by a return to a decline in cognitive function, although this decline was slower in those taking Cognex, compared to those taking a placebo.