Binswanger's Disease (Cont.)

Binswanger's Disease Treatment

There is no cure for Binswanger's disease; therefore, treatment for the condition is symptomatic, meaning that it is focused on treating the symptoms and complications that may occur as a result of Binswanger's disease, such as depression.
 
People with depression or anxiety may require antidepressant medications such as the serotonin-specific reuptake inhibitors (SSRIs) sertraline (Zoloft®) or citalopram (Celexa®). Atypical antipsychotic drugs, such as risperidone (Risperdal®) and olanzapine (Zyprexa®), can be useful in individuals with agitation and disruptive behavior. Recent drug trials involving memantine (Namenda®) have shown improved cognition and stabilization of global functioning and behavior.
 
The successful management of high blood pressure, high cholesterol, and diabetes can slow the progression of atherosclerosis, and subsequently slow the progress of Binswanger's disease. Because there is no cure, the best treatment is preventive, early in the adult years, by controlling risk factors such as high blood pressure, diabetes, and smoking.
 
(Click Atherosclerosis Prevention to learn more about ways to prevent atherosclerosis.)
 

Prognosis for People With Binswanger's Disease

Binswanger's disease is a slowly progressive condition for which there is no cure. Changes may be sudden or gradual and then progress in a stepwise manner. Binswanger's disease can often coexist with Alzheimer's disease.
 
Behaviors that slow the progression of high blood pressure, diabetes, and atherosclerosis -- such as eating a healthy diet and keeping healthy wake/sleep schedules, exercising, and not smoking or drinking too much alcohol -- can also slow the progression of Binswanger's disease.
 

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Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD